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Fig. 7. YXXG{Phi} and YXX{Phi} motifs are interchangeable in the P2X4 receptor. P2X4-GFP with residues YEQGL replaced by YQRLN (YQRL, above) was indistinguishable from wild type (see Fig. 5, WT). Mutation of Y378A abolished internalization (AQRL, below). Cells were co-stained for DNA (red). Bar, 10 µm.





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