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Fig. 1. The Hops gene. (A) Northern blot analysis of Hops mRNA extracted from rat at different times following PH (h PH). Normal liver (NL) was used as a control. rRNA of the same samples were used as a loading control. (B) Protein sequence of HOPS. The ubiquitin-like domain (102-175) is underlined; the proline-rich domain (176-183) is in bold; the putative NES is boxed. (C) Schematic representation of HOPS. The characteristic domains of the amino acid sequence are indicated. (D) Western blot analysis of HOPS during liver regeneration in mouse using a specific antibody. NL and liver after PH (minutes and hours PH). Anti-CREB was used as a loading control.





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