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Fig. 8. A schematic outline of the S. neurona cell cycle. (1) Merozoites infect a host cell and initiate intracellular development. For 2-3 days the nucleus cycles from mitosis (2) to interphase (3) growing in size and ploidy. Intranuclear microtubular structures are always evident either as full mitotic spindles (2) or as peculiar `mini-spindles' in interphase (3, constant kinetochore spindle association as drawn, is an attractive hypothesis but has not been experimentally confirmed yet). Concurrent with the last mitosis, budding (4) and cytokinesis (5) occur, giving rise to 64 merozoites (only 8 shown here for simplicity). Plastid (green) development mirrors nuclear (turquoise) events and both organelles are organized by centrosomes (black dots) and spindles (red). S, S phase; M, mitosis; B, budding.





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