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Fig. 3. {alpha}-Syn contributes to PP2A activation in MN9D and PC12 cells. (A) Cell lysates from MN9D cells and from induced PC12 cells were immunoprecipitated for the PP2A catalytic subunit. A representative immunoblot shows equivalent amounts of PP2A immunoprecipitated from all samples. (B) The activity of the immunoprecipitated PP2A was measured for MN9D cells (gray bars) and for induced PC12 cells (black bars). Plasmid, plasmid-transfected control cells; {alpha}-Syn; stably transfected {alpha}-Syn-overexpressing cells. Values are mean ± s.e.m. from three independent experiments. *P<0.05.





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