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Fig. 5. Co-activation of a JNK and a Nox pathway mimic the Rac mitogenic rescue. Active DA-MKK4, DA-MKK7 (A) and p47SD (B) partially rescue the Abl-PP-K G1 block. Quiescent NIH3T3 transfected with Abl-PP-K together or not with the indicated constructs were stimulated or not with PDGF in the presence of BrdU and proceeded as in Fig. 2. The mean±s.d. of the percentage of BrdU-positive cells present in expressing and non-expressing cells under the specified conditions is shown.





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