spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 6. Abl regulates PDGF-induced JNK and Nox activation. (A) Abl regulates PDGF-induced JNK activation. (Top panels) The level of active MAPK (pMAPK) and JNK (pJNK) from cells stimulated with PDGF (0-30 minutes). The level of MAPKs and JNK1 is also shown. (Bottom panels) The level of Jun and pS63-Jun (pJun) from indicated cell-lysates. (B,C) Abl regulates PDGF-induced Noxo2 (p47phox) membrane translocation. (B) Immunofluorescence localization of p47phox-GFP, actin structure and nuclei from indicated cells stimulated or not with PDGF as shown. (C) Statistic analysis of p47 membrane recruitment upon PDGF stimulation. Indicated quiescent cells transfected with p47phox-GFP were stimulated with PDGF for 5 minutes and the percentage of cells with p47 membrane localization was counted. The mean±s.d. (n=5) of the percentage of cells that exhibited p47-GFP at the membrane is shown.





Right arrow Return to article