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Fig. 8. Characterization of the interaction of the C-terminal region of filamin-C with deletion mutants of myotilin and FATZ-1 in yeast. +, growth; –, no growth, on selective media, tested as described in Materials and Methods and Fig. 4. The N-terminal regions of both myotilin and FATZ-1 interact with the C-terminal region of filamin-C. *As FATZ163-299 fused with the GAL4-BD caused auto-transactivation on both selective media, binding of FATZ163-299 to filamin-C was verified utilizing GAL4-AD protein of FATZ-1.





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