spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 3. Membrane fusion. (A) Putative model of SNARE-mediated membrane fusion. At stage I, Q- and R-SNAREs are separate from each other and the Q-SNARE syntaxin exists in its closed conformation. SNARE complex formation releases the Q-SNARE HABC N-terminal domain and is associated with vesicle docking (stage II). Several SNARE complexes may associate at the fusion site via their TMSs. Docking may result in hemifusion (III), which is followed by formation of lipidic (IV) or proteinaceous (V) fusion pores prior to full fusion (V). Note that proteins and membranes are not drawn to scale. (B) Lipid topology in hemifusion.





Right arrow Return to article