spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 7. CA-CamKII promotes the destruction of both cyclin B1 and securin. Eggs were microinjected with cRNA to cyclin B1::YFP or securin::CFP and then with cRNA to CA-CamKII. (A) APC/C activity increased following introduction of CA-CamKII as judged by the degradation of cyclin B1 (n=6). Cyclin B1 levels dropped to a minimum at the time of second polar body extrusion and levels remain low until pronuclei formation. Representative brightfield and cyclin B1::YFP images are shown at various times after injection as indicated. (B) A similar degradation profile for securin::CFP is also observed following introduction of CA-CamKII cRNA (n=10). (A and B) CA-CamKII cRNA was microinjected at t=0; second polar body extrusion (PB2; arrow); pronuclei formation (PN; arrowhead). Scale bar: 20 µm.





Right arrow Return to article