(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 4. Reorganisation of ER into sheets underlying the plasma membrane. (A) Confocal image of anisomycin-treated HeLa cells stained with an anti-KDEL antibody (red) and DAPI (blue). Arrowheads indicate extended areas of ER membrane at the cell periphery which are not in blebs and which are not associated with chromatin. Arrows indicate sheets of ER that end abruptly. Cell profiles are indicated by solid lines. Part of a non-apoptotic cell is present at the bottom, indicating the normal organisation of ER. Bar, 5 µm. (B-D) Magnified views from panel A, showing ER staining (left panels) and DAPI (right panels).