spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 3. Binding of soluble N-cadherin Fc to cell surface N-cadherin. Mutant or wild-type Fc fusion proteins were used to `stain' cell surface N-cadherin expressed by K562 transfectants. Binding was detected with FITC-labelled anti-Fc. The shaded profiles are negative controls using N-cadherin Fc with the mutation Asp134Ala. Results show that the affinity between wild-type cadherin molecules was too low to give detectable binding, whereas the interaction between Glu89Ala (E89A) and the Gly-Gly mutant (GG) gave strong staining.





Right arrow Return to article