JCS02578 Supplementary Material

Files in this Data Supplement:

• Supplemental Table - Adobe PDF

• Supplemental Figure 1 - Fig. S1. Sequence alignment of T. brucei SRP68 with its homologues. The alignment was performed using the ClustalW multiple sequence alignment program (http://npsa-pbil.ibcp.fr/cgi-bin/npsa_automat.pl?page=/NPSA/npsa_clustalwan.html). Residues red, green, and blue represent identity, similarity and weak similarity, respectively. Pink represents residues that are conserved between trypanosome species. The sequences were obtained from the following sources: Tbrucei, T. brucei, GeneDB accession number Tb04.29M18.150; Tcruzi, T. cruzi, GeneDB accession number Tc00.1047053504013.90; Lmajor, L. major, GeneDB accession number  LmjF34.2790; Hsapiens, Homo sapiens, TrEMBL accession number  SRP68_HUMAN; Dmelanogaster, D. melanogaster, TrEMBL accession number SRP68_DROME; Athaliana, A. thaliana, TrEMBL accession number Q9FH46_ARATH; Celegans, C. elegans, TrEMBL accession number SRP68_CAEEL.

• Supplemental Figure 2 - Fig. S2. Sequence alignment of T. brucei SRP72 with its homologues. Alignment analysis was performed as described in Fig. 1. The 7SL RNA binding domain is indicated in yellow. Red circles, residues thought to mediate interactions with other proteins. Residues highly conserved between trypanosome species are indicated in a box. The sequences were obtained from the following sources: Tbrucei, T. brucei, GeneDB accession number Tb10.61.0850; Tcruzi, T. cruzi, GeneDB accession number Tc00.1047053508897.20; Lmajor, L. major, GeneDB accession number  LmjF19.0790; Hsapiens, Homo sapiens, TrEMBL accession number  SRP72_HUMAN ; Dmelanogaster, D.melanogaster, TrEMBL accession number Q9VDK7_DROME; Athaliana, A.thaliana, TrEMBL accession number Q9FXD1_ARATH; Celegans, C. elegans, TrEMBL accession number SRP72_CAEEL.