spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 3. Model of the action of Halo-like proteins in bidirectional transport on MTs. (A) In the absence of Halo proteins, plus-end and minus-end motors alternate their binding to coordination machinery (possibly containing dynactin) and move RNA cargo towards either plus-ends or minus-ends of MTs. (B) Halo proteins change the steric properties of the coordination machinery, which weakens its binding to the minus-end motor and increases its binding to the plus-end motor, and results in the movement of the cargo towards the MT plus-end [adapted from Gross (Gross, 2003) and Gross et al. (Gross et al., 2003)].





Right arrow Return to article