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Fig. 4. Effect of Ror1 and Ror2 suppression by antisense oligonucleotide treatment on stage II hippocampal neurons. One-day cultured control (A,D,G,J), Ror1 sense-treated (B,E), Ror2 sense-treated (H,K), Ror1 antisense-treated (C,F) and Ror2 antisense-treated (I,L) hippocampal neurons were double stained with tubulin (A-C, G-I) and Ror1 (D-F) or Ror2 (J-L) antibodies. Ror1 and Ror2 suppression by the corresponding antisense oligonucleotide (arrows in F,L) was accompanied by the elongation of shorter and less branched minor processes (mp). Bar, 20 µm.





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