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Fig. 6. Tau interacts with GST-KLC1 and GST-KLC2. (A,B) Western blots of rat brain homogenate (A) or recombinant human tau (B) probed with a polyclonal antibody to tau after incubation with purified GST, GST-KLC1 or GST-KLC2 bound to glutathione-Sepharose beads. Both recombinant human tau and endogenous rat brain tau, or complexes containing rat brain tau, bind to GST-KLC1 and GST-KLC2, but not to purified GST.





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