Bves modulates epithelial integrity through an interaction at the tight junction
J Cell Sci Osler et al.
118: 4667
JCS02588 Supplementary Material
Files in this Data Supplement:
Supplemental Figure 1
-
FigS1. Localization of
Bves to cell-cell contacts is coincident with ZO-1 and AJ proteins.
Subconfluent MDCK cells were labeled with Bves and antibodies or stains
detecting vinculin (A), actin (B), E-cadherin (C), ZO-1 (D) and desmosomes (E).
(A,B) Bves is absent from immediate contacts as represented by actin and
vinculin (arrows). (C,D) Bves arrives at the cell membrane with AJ proteins and
ZO-1 (arrows). (E) Bves arrives prior to desmosomal proteins (arrows) at sites
of contact. Bars, (A-C) 10 mm;(D,E) 20 mm.