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Fig. 3. The dose-dependent effects of mßcd on CV-CV fusion. (A) Ca2+ activity curves (n=4) following treatments with various concentrations of mßcd as indicated. (B) Kinetics of CV-CV fusion treated as in A, triggered with 71±21 µM [Ca2+]free (n=3). (C) Total CV cholesterol after treatment with the indicated concentration of mßcd, expressed relative to untreated CVs. *Significant difference from control (P<0.05); **, ***, ****significant difference from control and all other conditions (P<0.001).





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