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Fig. 8. The effects of cholesterol oxidase activity on CV-CV fusion. (A) Ca2+ activity curves of CVs treated with 0 U/ml (n=3), 0.01 U/ml (n=3), 0.1 U/ml (n=3), or 1.0 U/ml cholesterol oxidase (n=3). Vertical dashed lines indicate the respective EC50 values. (B) Total cholesterol of CVs treated as indicated. Results are expressed as percent of untreated CVs; *, **significant difference from control and all other samples (P<0.005).





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