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Fig. 2. Phylogenetic analysis of the CZH1 (a) and CZH2 (b) domains. Multiple alignments were built using the CLUSTALW program and the distances between all pairs of sequences in the multiple alignment were determined (Thompson et al., 1994). Phylogenetic trees were generated using the neighbor-joining method (Saitou and Nei, 1987) and trees were drawn using the TREEVIEW program (Page, 1996). Bar, 0.1 nucleotide substitutions per site. At, Arabidopsis thaliana; Ce, Caenorhabditis elegans; Dd, Dictyostelium discoideum; Dm, Drosophila melanogaster; Hs, Homo sapiens; Sc, Saccharomyces cerevisiae.





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