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Fig. 8. Genome-wide distribution of transcriptional regulators in S. cerevisiae. (A) Solid symbols represent the number of transcription factors bound per promoter region (corresponding to the in-degree of the regulated gene). Open symbols represent the in-degree distribution of a comparable randomized network. (B) Distribution of the number of promoter regions bound per regulator (i.e. the out-degree distribution of transcription factors). Figure reproduced with permission from the American Association for the Advancement of Science (Lee et al., 2002).





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