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Fig. 1. Chemical structures of suramin and its naphthalene and benzene derivatives with sulfonic, carbonic or phosphonic acid substitutions. Suramin, NF449, NF023, NF058, NF078, NF110, NF305, NF307, NF506 are characterised by symmetrical aromatic structure with sulfonic acid substitutions. Symmetrical compounds NF068, NF542, NF710 present phosphonic and NF043, carbonic acid groups. ANTS and NF007 have sulfonic acid substitutions but lack bipolar structure. NN is an uncharged aromatic compound with symmetrical structure.





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