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Fig. 1. Cajal bodies (CBs) can associate with PML bodies. (Left) HeLa cells were transfected with GFP-coilin to mark CBs (green) and PML bodies were detected with anti-PML antibodies (red). (Right) CBs and PML bodies formed by ectopically expressed proteins can associate. HeLa cells were co-transfected with CFP-coilin (red) and YFP-Sp100 (to mark PML bodies, green). In both panels, DAPI staining was used to identify the nucleus and associated CBs and PML bodies are marked with arrows. Scale bar, 2 µm.





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