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Fig. 6. The p96 allele supports embryonic development. Offspring of p96/+ (A) or p67/+ (B) intercrosses were genotyped during development or at postnatal day 1 and/or 10. (A) p96 homozygotes were present at the expected rate at both stages during development. P10 pups were genotyped from females that were not simultaneously nursing a previous litter. From these females, p96/p96 pups were present at the expected mendelian ratio. (B) p67 homozygous embryos were present at expected mendelian rates at both E6.5 and E10.5, but by P1 and P10 there was a significant decline in the number of pups recovered (P=0.06 and P<0.001, respectively). Dashed line, expected recovery of homozygotes (25%); n value for each genotype is given within each bar.
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