spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 4. RRM3 mediates TIAR nuclear export. (A) Subcellular localization of TIAR-FLAG and TIAR{Delta}RRM3-FLAG mutant in Cos cells before and after actinomycin D (5 µg/ml) treatment for 3 hours. Cells were fixed, immunostained with anti-FLAG antibody, and analyzed by epifluorescence microscopy. (B) Schematic representation of NPc-NLS-FLAG constructs with or without different parts of the TIAR protein. Mutations in the NPc-RRM3mutRNP2-NLS-FLAG and NPc-RRM3mutRNP1-NLS-FLAG were: Y208D, C209R, G210P, G211P, I212D and G241P, Y242D, F244D, V245E, F247D, respectively. (C) Subcellular localization of proteins illustrated in B.





Right arrow Return to article