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Fig. 1. Calcium responses to LTD4, ATP and UDP following LTD4-induced CysLT1 receptor activation. (A) Representative traces of the [Ca2+]i transient induced by 10 nM LTD4 before and after an initial challenge with the same concentration of LTD4. (B,C) Representative traces of the [Ca2+]i transient induced by 10 µM ATP (B) and 100 µM UDP (C) (2nd challenge) before and after an initial challenge with 10 nM LTD4. (D) Values shown representative means of [Ca2+]i stimulation over basal (s/b) ± s.e.m. of at least three independent experiments.





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