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Fig. 3. Effect of GFX on CysLT1 receptor activation after LTD4, ATP and UDP challenge. Representative traces of the effect of increasing concentrations of GFX pretreatment (5 minutes) on [Ca2+]i transient induced by 10 nM LTD4 (2nd challenge) after an initial challenge with 10 µM ATP (A) and 100 µM UDP (B). (C) Values shown represent means of [Ca2+]i stimulation over basal (s/b) ± s.e.m. of at least three independent experiments.





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