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Fig. 5. Effect of postembryonic elt-1 RNAi on cuticle structure. (A) SEM of a normal adult worm showing lateral alae. (B) SEM of adult worm following postembryonic elt-1 RNAi showing loss of alae. (C) Adult worm expressing col-19::GFP from the kaIs12 transgene showing normal cuticle structure. (D) Adult hermaphrodite showing loss of alae and discontinuity of COL-19::GFP expression following elt-1 RNAi. (E) SEM of an adult hermaphrodite following elt-1 RNAi showing abnormal aggregation of material on the cuticle surface. (F) COL-19::GFP is present in material on the surface of an elt-1 RNAi adult hermaphrodite. An adult C. elegans hermaphrodite is approximately 1 mm in length. Individual cuticular annulae of an adult hermaphrodite are approximately 1 µm in width.





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