spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 4. Endocytotic vesicle capacitance is regulated by direct application of Ca2+ to inside-out excised membrane patches from INS-1 cells. (A) The frequency of endocytotic events in the excised patch was not changed significantly by bath application of Ca2+ (100 nM free, or 0.5 mM). (B) The size distribution, both as the square root of capacitance (fF1/2) and vesicle diameter, of endocytotic events observed in excised-patch recordings in the absence of Ca2+. (C) Bath application of a buffered 100 nM free-Ca2+ solution increased vesicle capacitance. Similar to the cell-attached experiments, this effect was bimodal, and did not occur upon application of 0.5 mM Ca2+. *, P<0.05; ***, P<0.001.





Right arrow Return to article