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Fig. 3. Expression and distribution pattern of different cell-adhesion receptors, BM components and hemidesmosomal proteins in regions of skin lacking ß4. (A-I) Cryosections of skin from a 2-day-old ß4flox/flox; K14-Cre mouse were processed for indirect immunofluorescence and visualized by confocal microscopy. Primary antibodies are against proteins indicated in the left lower corner of each image, and colors are coded according to FITC or Texas Red secondary antibodies. In all panels, the epidermis is at the top and the dermis at the bottom. Notice that only the distribution of the hemidesmosomal proteins plectin, BP180 and BP230 is affected by the absence of {alpha}6ß4.





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