(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 6. RasV12-mediated induction of MMP-9 mRNA accumulation is
3ß1-dependent. (A) MK+/+ and MK/ cells were infected with adenovirus expressing either ß-galactosidase as a control ( lanes) or RasV12 (+ lanes), then cultured on LN-5 ECM for 48 hours in serum-free medium. Total RNA was isolated and RT-PCR was performed to compare MMP-9 and ß-actin mRNA levels. (B) Signals for MMP-9 mRNA and ß-actin mRNA were quantified; graphs depict relative MMP-9 mRNA levels for each sample, after normalization to ß-actin mRNA. Data are presented as the mean±s.e.m. for three separate experiments; *P<0.05, two-way ANOVA with Newman Keuls post-hoc test.