spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 1. The expression of distinct Dyn3 variants induces profoundly different postsynaptic morphologies. (A,C) Neurons transfected with Dyn3aaa-GFP produce numerous mushroom-shaped dendritic spines by 18DIV (arrows in A). (B,D) Neurons expressing Dyn3baa-GFP exhibit morphologically immature dendritic spines at a mature culture age, with long filopodia remaining as the dominant structures instead of spines (arrows in B). (E,F) Although Dyn3aaa- and Dyn3baa-expressing neurons appear different at 18DIV, they exhibit remarkably similar morphologies at 11DIV, when filopodia normally persist. Images in C-F represent CFP fluorescence from Dyn3-spliceoform-co-transfected cells captured by confocal microscopy. Scale bars, 5 µm.





Right arrow Return to article