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Fig. 8. Schematic representation of the multiple PDZ domains of INAD. The principal binding protein partners that are known to interact with INAD and the PDZ domains involved are shown; TRP-TRP channel; PKC eye-enriched protein kinase C and PLCß-NORPA. Only key interactions about which there is general agreement among workers in the field are shown. The positions of point mutations in several INAD alleles including InaD1, InaD2, InaDP215, su(1) and su(100) are shown with respect to the PDZ domains.





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