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Fig. 6. Phosphoprotein comparisons of normal and ${gamma}$ SG-deficient TA muscle. (A) Immunoblots of tissue lysates show significant activation of ERK-1 and downregulation of adducin- ${gamma}$ phosphorylation with no changes in cofilin in ${gamma}$ SG^–/– tissue compared with control tissue. (B) Blots of stretched and unstretched ${gamma}$ SG^–/– tissue show hyperactivation of p38 MAPK, ERK1/2, MAPKAP2 and Smad1 in stretched tissue.

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