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Fig. 3. Bcl6–/– macrophages have reduced motility. Approximately 1x105 BMM were added to 8 µm pore-size inserts in either the presence (chemokinesis, black bars) or absence (chemotaxis, gray bars) of CSF1 and then placed in CSF1-containing wells for 3 hours. Migrated cells were scored and normalized to the total cell number in an insert-free well. The means of four fields per insert were averaged and the results shown are representative of three independent experiments (mean±s.e.m.). Differences in proliferation rates (unpublished data) would not have significantly contributed to the results of this 3-hour experiment.





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