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Fig. 7. Sequence motifs conserved among known vertebrate GluR tail sequences. (A) The predicted amino acid sequences of six vertebrate GluR1, five vertebrate GluR2 (long tail isoform) and five vertebrate GluR4 tail sequences, aligned by CLUSTALW. (B) The predicted amino acid sequences of five vertebrate GluR2, eight vertebrate GluR3 and a rat GluR4 (short tail isoform) tail sequences, aligned by CLUSTALW. (C) The predicted amino acid sequences of rat GluR5-1, GluR6 and GluR7 kainate receptors, aligned by CLUSTALW. (D) The predicted amino acid sequences of rat, mouse, and human KA-1 and KA-2 kainate receptors, aligned by CLUSTALW. For all alignments, the majority consensus sequence is highlighted in black. Similarities are highlighted with gray. Lines above a sequence demarcate the conserved sequence motifs identified in Fig. 6D,E.





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