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Fig. 4. Neutralization of SDF-1 activity impairs keratinocyte proliferation (A) Phase contrast microscopy demonstrating the inhibitory effect of neutralizing antibodies against either SDF-1 (10 µg/ml) or its receptor CXCR4 (5 µg/ml) on keratinocyte growth. Individual islands are outlined with dashed lines. (B) Proliferating cells and colony size were quantified as in Fig. 3B.