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Fig. 1. Western-blot analysis of CPA and pro-CPA in peritoneal cells from cathepsin-deficient mice. Peritoneal-cell extracts from mice deficient in cathepsin B (A), cathepsin L (B), cathepsin D (C) or cathepsin E (D), and extracts from corresponding wild-type or heterozygous mice, were subjected to western-blot analysis using a an antiserum that recognizes both pro-CPA (~55 kDa) and processed CPA (~35 kDa). Cat, cathepsin.





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