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Fig. 1. Localization of RhoA and DNA during cytokinesis in HeLa cells. In interphase, RhoA (upper panels) distributes diffusely in the cytoplasm. After onset of mitosis, RhoA begins to accumulate at the cell cortex (metaphase). Accumulation of RhoA at the equatorial cortex is detected before furrowing (arrowhead) and after which it forms a ring structure at the cleavage furrow (anaphase to telophase). Finally, RhoA localizes to the midbody (late telo.). Lower panels show DNA staining. Bar, 10 µm.





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