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Fig. 5. Rupture force of a single cadherin-cadherin bond as a function of reproach velocity. (A) Distribution of rupture forces to break a single E-cadherin-E-cadherin bond between apposing cells subjected to different reproach velocities, representing at least 500 cell-cell contacts at each velocity. (B) Distribution of rupture forces to break a single N-cadherin-N-cadherin bond at different reproach velocities, representing at least 500 cell-cell contacts at each velocity. Immunofluorescence micrographs of N-cadherin-expressing CHO cells (C) and E-cadherin-expressing CHO cells (D). Bar, 10 µm.





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