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Figure 7


Fig. 7. Microdomain-associated CD81 supports P. yoelii sporozoite infection. (A) Effects of increasing concentrations of mAbs MT81 (solid squares) and MT81w (open squares) on P. yoelii infection of Hepa1-6 cells, expressed as the mean percentage of inhibition in triplicate wells (± s.d.). (B) Untreated (control) and MßCD/cholesterol treated Hepa1-6 cells were infected with P. yoelii sporozoites in the presence of MT81 and MT81w mAbs. Results are expressed as the mean percentage inhibition in triplicate wells (± s.d.), as compared to wells without mAbs.





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