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Figure 7


Fig. 7. GABAB receptors are internalized by clathrin-independent endocytosis. Cells blocked in their phagocytic activity by trifluoperazine (2.5 µg/ml for 15 minutes) were incubated for 5 minutes at 25°C with anti-GABAB receptor antibody (dilution 1:100) and dextran-coupled Texas-Red (0.02% w/v). Colocalization of GABAB receptors and dextran is seen inside the vesicles located on the cell membrane (yellow). Bar, 20 µm.





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