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Figure 1


Fig. 1. Knocked-in {alpha}3 connexin suppresses the severe cataract caused by the {alpha}8-G22R mutation. Comparison of three compound mutant lenses of mice aged 3 weeks. (A) The {alpha}3(-/-) {alpha}8(KI{alpha}3/-) lens is transparent. (B) The {alpha}3(-/-) {alpha}8(G22R/-) lens has severe cataract with posterior rupture. (C) The {alpha}3(-/-) {alpha}8(G22R/KI{alpha}3) lens is intact with only a very mild nuclear cataract.





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