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Figure 9


Fig. 9. Ultrastructure of MTJs in muscle from 3-week-old wild-type, mdx, {alpha}7-/- and mdx/{alpha}7-/- mice. The sarcolemma of the MTJs of wild-type and mdx mice is highly folded, increasing the surface area between muscle and tendon (arrows); the extracellular matrix at this site is highly organized and electron-dense. By contrast, MTJs of {alpha}7-/- and mdx/{alpha}7-/- mice show little or no sarcolemmal folding (arrows) and the extracellular matrix appeared less dense and organized compared with those of wild-type and mdx mice (arrowheads). Bar, 1 µm.





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