spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 5


Fig. 5. Spermine blockade of gap junctional currents in N2a cells expressing wild-type (wt) or mutant Cx40. 2 mM spermine was applied unilaterally (in one pipet) during recording of a family of junctional currents. (A) Currents between a pair of cells (stably) expressing wtCx40 were blocked when Vj was positive (center). (B) Currents between a pair of cells (transiently) expressing Cx40E12S,E13G were not affected by 2 mM spermine. (C) Currents between a pair of cells co-expressing wtCx40 (stably) and Cx40E12S,E13G (transiently) were not affected by 2 mM spermine. (D) Currents between a pair of cells co-expressing wtCx40 (stably) and Cx43D12S,K13G (transiently) were slightly affected by 2 mM spermine.





Right arrow Return to article