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Figure 6


Fig. 6. Overexpression of dominant-negative FADD can inhibit apoptosis in MCF-10A cells treated with MLCK or actin polymerization inhibitors. FACS analysis of MCF-10A (A) and MCF-10A Ras-transformed (B) cells expressing pBabe DN FADD after plating on polyHEMA or treatment with ML-7, ML-9 or Y-27632 for 16 hours. Results are the mean ± s.e.m. of at least three experiments.





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