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Figure 9


Fig. 9. Spikes enhance interaction between apoptotic cells and phagocytes. (A) Proportion of THP-1 macrophages interacting (bound and engulfed) and engulfing apoptotic A431 cells. Target cells were generated in the absence or presence of nocodazole. Shown are means (± s.e.m.) of triplicate samples from a single representative experiment (statistical analysis by Student's t-test). (B,C) Wide-field images of CellTracker-labelled apoptotic A431 cells (arrowheads) interacting with THP-1 macrophages (asterisks). Zoomed images of the boxed areas are shown in the bottom panels of B and C. Bars=10 µm (zoom=5 µm).





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