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Figure 2


Fig. 2. Protein distribution in ICF and control G2 nuclei. (A) ATRX and PML proteins colocalise in the giant HP1-PML body and normal PML-NBs. A weak diffuse ATRX signal is also detectable in the nucleoplasm of ICF and control nuclei (PML, green; ATRX, red; nuclei, blue with DAPI). (B) Other proteins colocalise within the giant body as shown on ICF nuclei immunostained with antibodies against PML and DAXX, PML and BLM, PML and TOPOIII{alpha}, CBP and SUMO.





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