JCS02980 Supplementary Material

Files in this Data Supplement:

• Supplemental Table 1 - Adobe PDF

• Supplemental Table 2 - Adobe PDF

• Supplemental Figure 1 -

  Fig. S1. Expanded analysis of Ferlin proteins and C2 domain phylogeny. Ferlin protein diagrams.

• Supplemental Figure 2 -

  Fig. S2. Expanded analysis of Ferlin proteins and C2 domain phylogeny. Neighbor joining tree. Values on branches indicate strength of bootstrap support, and are only shown for major clades. * indicates bootstrap values fell below 50%. Accession numbers for Ferlin protein sequences are indicated in Table S1.

• Supplemental Figure 3 -

  Fig. S3. Diagram of fer-1 alternative transcripts. Shaded boxes represent the exons in (A) full-length fer-1 and (B-C) two additional transcripts identified by RT-PCR. The cDNA size (kb) and predicted protein molecular weight (MW) for each is listed to the right. The region encoding the anti-DysfNC antigenic site is indicated (dashed line) below the figure. The location of the fer-1(hc47) mutation that has a stop codon and is used as a negative control is also indicated above.