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Figure 2


Fig. 2. Co-localization of JPO2 with wild-type and NLS-deficient p75. (A) EGFP-JPO2 accumulates in nuclei with a heterogeneous distribution pattern. (B) EGFP-JPO2 and HcRed1-p75 co-localize in cell nuclei. (C) EGFP-GST-p75K150A (K150A) sequesters HcRed1-JPO2 to the cell cytoplasm. (D) Co-localization of EGFP-p75326-530 (p75/Ct) and HcRed1-JPO2. Images were acquired 24 hours post-transfection. Bars, 10 µm.





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