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Fig. 9. Adenovirus infection does not lead to a marked downturn in rRNA synthesis. Total RNA was extracted from infected HeLa cells at the times post-infection indicated, along with 2 mock-infected control samples taken at 8 hours post-mock infection (Con1) and 30 hours post-mock infection (Con2). (A) Each sample was assayed for rRNA synthesis by S1 nuclease protection assay for the 5' end of pre-rRNA. (B) Total RNA present in each sample, demonstrating similar quantities of RNA were present in each S1 nuclease protection assay.